SCHEMBL2915802

SCHEMBL2915802

Cc1ccc(C(=O)NCCCCCCCC(=O)O)c(O)c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 2/20 0.55
EGLN1 Q9GZT9 1/20 0.52
POLB P06746 3/20 0.51
ALDH1A1 P00352 2/20 0.51
KDM4E B2RXH2 1/20 0.51
NPC1 O15118 2/20 0.50
RAB9A P51151 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
ALOX5 P09917 1/20 0.50
HDAC3 O15379 1/20 0.49
HDAC1 Q13547 1/20 0.49
PTGS1 P23219 1/20 0.49
PTGS2 P35354 1/20 0.49
APP P05067 3/20 0.49
NAAA Q02083 1/20 0.49
CYP1A2 P05177 1/20 0.49
CYP2C9 P11712 1/20 0.49
CYP2C19 P33261 1/20 0.49
LMNA P02545 1/20 0.48
GAA P10253 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31661859 1.00 MAPK1 (0.55) MAPK1EGLN1POLBALDH1A1KDM4E
SCHEMBL31661686 0.89 NAAA (0.57) MAPK1POLBALDH1A1KDM4ENPC1
SCHEMBL2164508 0.89 NAAA (0.57) MAPK1POLBALDH1A1KDM4ENPC1
SCHEMBL5656378 0.86 MAPK1 (0.58) MAPK1POLBALDH1A1KDM4EALOX5
SCHEMBL11026787 0.86 MAPK1 (0.58) MAPK1POLBALDH1A1KDM4EALOX5
SCHEMBL13577934 0.84 NAAA (0.64) EGLN1ALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL12434386 0.84 POLB (0.63) MAPK1POLBALDH1A1NPC1RAB9A
SCHEMBL5654581 0.83 MAPK1 (0.55) MAPK1POLBALDH1A1KDM4EALOX5
SCHEMBL4624092 0.83 MAPK1 (0.55) MAPK1POLBALDH1A1KDM4EALOX5
SCHEMBL16545132 0.83 MAPK1 (0.55) MAPK1POLBALDH1A1KDM4EALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025151884-A1 USE OF GLYCOSAMINOGLYCAN SULFATED POLYSACCHARIDES SUCH AS SODIUM PENTOSAN POLYSULFATE IN COMBINATION WITH PERMEATION AGENTS TO TREAT ALZHEIMER'S DISEASE PARSONS C LOWELL (US) 2025-07-17 WO claimed
US-20170189443-A1 COMPOSITIONS AND METHODS FOR TREATMENT OF DISEASES AND CONDITIONS EMPLOYING ORAL ADMINISTRATION OF SODIUM PENTOSAN POLYSULFATE AND OTHER PENTOSAN POLYSULFATE SALTS PLATINUM MONTAUR LIFE SCIENCES, LLC AND AS AGENT (KY) 2017-07-06 US claimed
EP-3110427-A1 COMPOSITIONS OF PENTOSAN POLYSULFATE SALTS FOR ORAL ADMINISTRATION AND METHODS OF USE Urigen Pharmaceuticals, Inc. (US) 2017-01-04 EP claimed
WO-2015127416-A1 COMPOSITIONS OF PENTOSAN POLYSULFATE SALTS FOR ORAL ADMINISTRATION AND METHODS OF USE URIGEN PHARMACEUTICALS, INC. (US) 2015-08-27 WO claimed
WO-2025151884-A1 USE OF GLYCOSAMINOGLYCAN SULFATED POLYSACCHARIDES SUCH AS SODIUM PENTOSAN POLYSULFATE IN COMBINATION WITH PERMEATION AGENTS TO TREAT ALZHEIMER'S DISEASE PARSONS C LOWELL (US) 2025-07-17 WO disclosed
US-20170189443-A1 COMPOSITIONS AND METHODS FOR TREATMENT OF DISEASES AND CONDITIONS EMPLOYING ORAL ADMINISTRATION OF SODIUM PENTOSAN POLYSULFATE AND OTHER PENTOSAN POLYSULFATE SALTS PLATINUM MONTAUR LIFE SCIENCES, LLC AND AS AGENT (KY) 2017-07-06 US disclosed
EP-1100522-B1 PULMONARY DELIVERY OF ACTIVE AGENTS EMISPHERE TECH INC (US) 2016-12-07 EP disclosed
EP-1100522-B1 PULMONARY DELIVERY OF ACTIVE AGENTS EMISPHERE TECH INC (US) 2016-12-07 EP disclosed
US-8785381-B2 Oral GLP-1 formulations EMISPHERE TECHNOLOGIES, INC. (US) 2014-07-22 US disclosed
US-8785381-B2 Oral GLP-1 formulations EMISPHERE TECHNOLOGIES, INC. (US) 2014-07-22 US disclosed
EP-1696960-B1 INTRANASAL ADMINISTRATION OF GLUCOSE-REGULATING PEPTIDES AMYLIN PHARMACEUTICALS INC (US) 2010-09-08 EP disclosed
US-20100160556-A1 GLP-1 Fusion Peptides Conjugated to Polymer(s), Their Production and Use BIOCOMPATIBLES UK LTD. (GB) 2010-06-24 US disclosed
US-6693073-B2 ADMINISTERING VIA THE PULMONARY ROUTE FOMULATION COMPRISING ACTIVE AGENT AND CARRIER COMPRISING AN ACYLATED AMINO ACID, A SULFONATED AMINO ACID, A POLYAMINO ACID OR MIXTURES EMISPHERE TECHNOLOGIES, INC. 2004-02-17 US disclosed
US-20030072740-A1 Pulmonary delivery of active agents EMISPHERE TECHNOLOGIES, INC. 2003-04-17 US disclosed
EP-1100522-A4 PULMONARY DELIVERY OF ACTIVE AGENTS EMISPHERE TECH INC (US) 2003-01-08 EP disclosed
US-6440929-B1 ACYLATED AMINO ACID OR A SULFONATED AMINO ACID EMISPHERE TECHNOLOGIES, INC. 2002-08-27 US disclosed
EP-1100522-A1 PULMONARY DELIVERY OF ACTIVE AGENTS Emisphere Technologies, Inc. (US) 2001-05-23 EP disclosed
WO-2000006184-A1 PULMONARY DELIVERY OF ACTIVE AGENTS EMISPHERE TECHNOLOGIES, INC. (US) 2000-02-10 WO disclosed
US-5962710-A Method of preparing salicyloylamino acids EMISPHERE TECHNOLOGIES, INC. (US) 1999-10-05 US disclosed
WO-1998050341-A1 METHOD OF PREPARING SALICYLOYLAMINO ACIDS EMISPHERE TECHNOLOGIES, INC. (US) 1998-11-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100160556-A1 GLP-1 Fusion Peptides Conjugated to Polymer(s), Their Production and Use IAPP, GIPR, GLP1R MAPK1 2756/4885EGLN1 2657/4885POLB 4791/4885
US-20030072740-A1 Pulmonary delivery of active agents ANXA11, ANXA1, PIGS MAPK1 4731/4885EGLN1 1212/4885POLB 3569/4885
US-20170189443-A1 COMPOSITIONS AND METHODS FOR TREATMENT OF DISEASES AND CONDITIONS EMPLOYING ORAL ADMINISTRATION OF SODIUM PENTOSAN POLYSULFATE AND OTHER PENTOSAN POLYSULFATE SALTS SI, SLC20A1, SLC20A2 MAPK1 3137/4885EGLN1 3371/4885POLB 2682/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.