Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 1/20 | 0.55 |
| ▸ | RPS6KB2 | Q9UBS0 | 6/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL327089 | 0.77 | IKBKB (0.63) | IKBKBNPC1RAB9ALMNACASP1 | |
| SCHEMBL30499579 | 0.77 | IKBKB (0.63) | IKBKBNPC1RAB9ALMNACASP1 | |
| SCHEMBL28531922 | 0.74 | RPS6KB2 (0.62) | RPS6KB2NPC1RAB9AATMHSD17B10 | |
| SCHEMBL17049363 | 0.74 | RPS6KB2 (0.57) | RPS6KB2NPC1RAB9AATMSRPK1 | |
| SCHEMBL29636225 | 0.74 | RPS6KB2 (0.57) | RPS6KB2NPC1RAB9AATMSRPK1 | |
| SCHEMBL5190972 | 0.73 | KDM4E (0.74) | ATMHSD17B10LMNAGLAALDH1A1 | |
| SCHEMBL4341036 | 0.72 | KDM4E (0.50) | IKBKBRPS6KB2NPC1SRPK1HSD17B10 | |
| SCHEMBL16027135 | 0.72 | RPS6KB2 (0.74) | RPS6KB2NPC1RAB9AATMSRPK1 | |
| SCHEMBL31393470 | 0.72 | RPS6KB2 (0.74) | RPS6KB2NPC1RAB9AATMSRPK1 | |
| SCHEMBL2099350 | 0.72 | IKBKB (0.69) | IKBKBHSD17B10GLAALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025151311-A1 | NICOTINAMIDE DERIVATIVES | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2025-07-17 | — | — | WO | disclosed |