Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 2/20 | 0.63 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | PARP1 | P09874 | 2/20 | 0.47 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.47 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.47 |
| ▸ | GALR3 | O60755 | 1/20 | 0.46 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.44 |
| ▸ | DHODH | Q02127 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30499579 | 1.00 | IKBKB (0.63) | IKBKBPDE10ARXFP1PARP1NCOA1 | |
| SCHEMBL3912410 | 0.86 | PDE10A (0.56) | IKBKBPDE10AKDM4ENPC1GAA | |
| SCHEMBL27720177 | 0.86 | PDE10A (0.56) | IKBKBPDE10AGALR3NR2F2KDM4E | |
| SCHEMBL28258899 | 0.81 | PDE4B (0.46) | IKBKBRXFP1PARP1NCOA1NCOA3 | |
| SCHEMBL29725411 | 0.81 | IKBKB (0.56) | IKBKBRXFP1PARP1KDM4ERAB9A | |
| SCHEMBL30843886 | 0.80 | L3MBTL1 (0.58) | IKBKBPARP1KDM4ENPC1GAA | |
| SCHEMBL27992695 | 0.80 | PDE10A (0.53) | PDE10AKDM4EGAAALDH1A1HPGD | |
| SCHEMBL9375622 | 0.78 | PARP1 (0.46) | IKBKBPARP1KDM4EALDH1A1BCAT2 | |
| SCHEMBL10473755 | 0.78 | IKBKB (0.65) | IKBKBPARP1NCOA1NCOA3GALR3 | |
| SCHEMBL529972 | 0.78 | MEN1 (0.57) | IKBKBPDE10ANPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3312175-B1 | HETEROARYL DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING DISEASES ASSOCIATED WITH PI3 KINASES, CONTAINING SAME AS ACTIVE INGREDIENT | KOREA RES INST CHEMICAL TECH (KR) | 2020-07-22 | — | — | EP | disclosed |
| CN-108358842-A | His quinoline not crystal form of moral and preparation method thereof, its pharmaceutical composition and purposes | 杭州普晒医药科技有限公司 | 2018-08-03 | — | — | CN | disclosed |
| CN-105367492-B | Taquinimod crystal form, preparation method, pharmaceutical composition and application thereof | 杭州普晒医药科技有限公司 | 2018-07-03 | — | — | CN | disclosed |
| EP-2590949-A1 | METHOD FOR MANUFACTURING OF QUINOLINE-3-CARBOXAMIDES | Active Biotech AB (SE) | 2013-05-15 | — | — | EP | disclosed |
| WO-2012004338-A1 | METHOD FOR MANUFACTURING OF QUINOLINE-3-CARBOXAMIDES | ACTIVE BIOTECH AB (SE) | 2012-01-12 | — | — | WO | disclosed |
| US-20080026427-A1 | HUMAN cDNAs AND PROTEINS AND USES THEREOF | SERONO GENETICS INSTITUTE S.A. (FR) | 2008-01-31 | — | — | US | disclosed |
| US-20070292885-A1 | HUMAN CDNAS AND PROTEINS AND USES THEREOF | GENSET, S.A. (FR) | 2007-12-20 | — | — | US | disclosed |
| EP-1867633-A1 | Polyamine analogues as therapeutic and diagnostic agents | MediQuest Therapeutics, Inc. (US) | 2007-12-19 | — | — | EP | disclosed |
| US-7291495-B2 | β-Secretase variant | SERONO GENETICS INSTITUTE S.A. (FR) | 2007-11-06 | — | — | US | disclosed |
| US-7285631-B2 | Human cDNAs and proteins and uses thereof | SERONO GENETICS INSTITUTE S.A. (FR) | 2007-10-23 | — | — | US | disclosed |
| WO-2003014151-A2 | HUMAN SECRETED PROTEINS, THEIR ENCODING POLYNUCLEOTIDES, AND USES THEREOF | GENSET S.A. (FR) | 2003-02-20 | — | — | WO | disclosed |
| US-20030027248-A1 | Human cDNAs and proteins and uses thereof | GENSET, S.A. (FR) | 2003-02-06 | — | — | US | disclosed |
| US-20030027161-A1 | Human cDNAs and proteins and uses thereof | GENSET, S.A. (FR) | 2003-02-06 | — | — | US | disclosed |
| WO-2002094864-A2 | HUMAN CDNAS AND PROTEINS AND USES THEREOF | GENSET S.A. (FR) | 2002-11-28 | — | — | WO | disclosed |
| US-20020102604-A1 | Full-length human cDNAs encoding potentially secreted proteins | SERONO GENETICS INSTITUTE S.A. (FR) | 2002-08-01 | — | — | US | disclosed |
| WO-2001092218-A2 | POLYAMINE ANALOGUES AS THERAPEUTIC AND DIAGNOSTIC AGENTS | ORIDIGM CORPORATION (US) | 2001-12-06 | — | — | WO | disclosed |
| EP-1085011-A1 | Novel polyamine analogues as therapeutic and diagnostic agents | ORIDIGM CORPORATION (US) | 2001-03-21 | — | — | EP | disclosed |
| US-6172261-B1 | BIOSYNTHESIS USING CHAIN EXTENSION | ORIDIGM CORPORATION | 2001-01-09 | — | — | US | disclosed |
| EP-1001927-A2 | NOVEL POLYAMINE ANALOGUES AS THERAPEUTIC AND DIAGNOSTIC AGENTS | ORIDIGM CORPORATION (US) | 2000-05-24 | — | — | EP | disclosed |
| WO-1999003823-A2 | NOVEL POLYAMINE ANALOGUES AS THERAPEUTIC AND DIAGNOSTIC AGENTS | ORIDIGM CORPORATION (US) | 1999-01-28 | — | — | WO | disclosed |