Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 5/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.34 |
| ▸ | GAK | O14976 | 1/20 | 0.34 |
| ▸ | RPS6KA4 | O75676 | 1/20 | 0.34 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.34 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.34 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.34 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.34 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.34 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.34 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.34 |
| ▸ | COQ8A | Q8NI60 | 1/20 | 0.34 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.34 |
| ▸ | STK36 | Q9NRP7 | 1/20 | 0.34 |
| ▸ | NLK | Q9UBE8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31662015 | 0.95 | SCN9A (0.36) | SCN9APDE4DMAPK14GAKRPS6KA4 | |
| SCHEMBL31662522 | 0.95 | SCN9A (0.36) | SCN9APDE4DMAPK14GAKRPS6KA4 | |
| SCHEMBL31661963 | 0.95 | SCN9A (0.36) | SCN9APDE4DMAPK14GAKRPS6KA4 | |
| SCHEMBL31662160 | 0.94 | SCN9A (0.36) | SCN9APDE4DCD38OPRM1OPRD1 | |
| SCHEMBL31662508 | 0.92 | CD38 (0.37) | SCN9AMAPK14GAKRPS6KA4PRKD3 | |
| SCHEMBL31662467 | 0.91 | CD38 (0.37) | SCN9APDE4DMAPK14GAKRPS6KA4 | |
| SCHEMBL31662176 | 0.90 | SCN9A (0.39) | SCN9APDE4DCD38HRH3OPRM1 | |
| SCHEMBL31662228 | 0.90 | SCN9A (0.39) | SCN9AMAPK8CD38OPRM1OPRD1 | |
| SCHEMBL31662072 | 0.90 | SCN9A (0.39) | SCN9APDE4DMAPK14CD38HRH3 | |
| SCHEMBL31662186 | 0.89 | CHEK2 (0.39) | SCN9AMAPK14HRH3OPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | claimed |
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | disclosed |