Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 5/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 8/20 | 0.34 |
| ▸ | PDE4A | P27815 | 2/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.34 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 3/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | GAK | O14976 | 1/20 | 0.32 |
| ▸ | RPS6KA4 | O75676 | 1/20 | 0.32 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.32 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.32 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.32 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31662015 | 1.00 | SCN9A (0.36) | SCN9AMAPK14PDE4DPDE4APDE4B | |
| SCHEMBL31662522 | 1.00 | SCN9A (0.36) | SCN9AMAPK14PDE4DPDE4APDE4B | |
| SCHEMBL31661947 | 0.95 | SCN9A (0.36) | SCN9AMAPK14PDE4DPIM1OPRM1 | |
| SCHEMBL31661893 | 0.90 | SCN9A (0.38) | SCN9APDE4DPDE4APDE4BPDE4C | |
| SCHEMBL31662085 | 0.90 | SCN9A (0.38) | SCN9APDE4DPDE4APDE4BPDE4C | |
| SCHEMBL31662160 | 0.89 | SCN9A (0.36) | SCN9APDE4DPIM1OPRM1OPRD1 | |
| SCHEMBL31662508 | 0.88 | CD38 (0.37) | SCN9AMAPK14PIM1GAKRPS6KA4 | |
| SCHEMBL31662228 | 0.87 | SCN9A (0.39) | SCN9AOPRM1OPRD1OPRK1MAPK8 | |
| SCHEMBL31662467 | 0.87 | CD38 (0.37) | SCN9AMAPK14PDE4DGAKRPS6KA4 | |
| SCHEMBL31661933 | 0.86 | SCN9A (0.39) | SCN9AOPRM1OPRD1OPRK1MAPK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | claimed |
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | disclosed |