Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 6/20 | 0.39 |
| ▸ | CHEK2 | O96017 | 3/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
| ▸ | TYK2 | P29597 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.33 |
| ▸ | CD38 | P28907 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31661933 | 0.95 | SCN9A (0.39) | SCN9ACHEK2KDM1AMAPK8CTSS | |
| SCHEMBL31661947 | 0.90 | SCN9A (0.36) | SCN9AMAPK8OPRM1OPRD1OPRK1 | |
| SCHEMBL31661975 | 0.90 | CHEK2 (0.41) | SCN9ACHEK2KDM1AJAK2JAK1 | |
| SCHEMBL31662186 | 0.89 | CHEK2 (0.39) | SCN9ACHEK2OPRM1OPRD1OPRK1 | |
| SCHEMBL31662522 | 0.87 | SCN9A (0.36) | SCN9AMAPK8OPRM1OPRD1OPRK1 | |
| SCHEMBL31662015 | 0.87 | SCN9A (0.36) | SCN9AMAPK8OPRM1OPRD1OPRK1 | |
| SCHEMBL31661963 | 0.87 | SCN9A (0.36) | SCN9AMAPK8OPRM1OPRD1OPRK1 | |
| SCHEMBL31661895 | 0.86 | PIK3CD (0.39) | SCN9ACHEK2OPRM1OPRD1OPRK1 | |
| SCHEMBL31662540 | 0.86 | GPR119 (0.43) | CHEK2 | |
| SCHEMBL31662603 | 0.84 | SCN9A (0.38) | SCN9AOPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | claimed |
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | disclosed |