Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 4/20 | 0.36 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 3/20 | 0.34 |
| ▸ | JAK3 | P52333 | 3/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | SYK | P43405 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CD38 | P28907 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 2/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.31 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.31 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31662165 | 0.94 | IRAK4 (0.37) | IRAK4TBK1JAK1JAK3SCN9A | |
| SCHEMBL31661929 | 0.90 | IRAK4 (0.37) | IRAK4TBK1JAK1JAK3SCN9A | |
| SCHEMBL31662279 | 0.89 | IRAK4 (0.37) | IRAK4TBK1JAK1JAK3SCN9A | |
| SCHEMBL31662162 | 0.89 | IRAK4 (0.37) | IRAK4TBK1JAK1JAK3SCN9A | |
| SCHEMBL31662135 | 0.89 | IRAK4 (0.37) | IRAK4TBK1JAK1JAK3SCN9A | |
| SCHEMBL31662113 | 0.88 | SCN9A (0.39) | IRAK4SCN9AROCK2SYKCD38 | |
| SCHEMBL31662142 | 0.87 | IRAK4 (0.39) | IRAK4TBK1MAPK1PDE4B | |
| SCHEMBL31662129 | 0.87 | MAPK1 (0.38) | IRAK4TBK1JAK1JAK3SYK | |
| SCHEMBL31661945 | 0.86 | LRRK2 (0.36) | SCN9ALRRK2MAPK1CD38 | |
| SCHEMBL31662428 | 0.86 | DHODH (0.37) | LRRK2MAPK1CD38 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | claimed |
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | disclosed |