Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
| ▸ | HAO1 | Q9UJM8 | 2/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | MIF | P14174 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.34 |
| ▸ | DRD4 | P21917 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | CD38 | P28907 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | HIPK4 | Q8NE63 | 1/20 | 0.33 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.33 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.33 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.33 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.33 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.33 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.33 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31661945 | 0.93 | LRRK2 (0.36) | HAO1LRRK2MAPK14DRD4MAPK1 | |
| SCHEMBL31662165 | 0.92 | IRAK4 (0.37) | LRRK2CD38 | |
| SCHEMBL31662770 | 0.91 | CD38 (0.36) | LRRK2MAPK14MAPK1CD38HIPK4 | |
| SCHEMBL31662475 | 0.90 | GCK (0.34) | DHODHMIFMAPK1KDM4E | |
| SCHEMBL31662412 | 0.89 | DRD4 (0.35) | DHODHHAO1LRRK2MIFDRD4 | |
| SCHEMBL31662086 | 0.88 | LRRK2 (0.34) | HAO1LRRK2MAPK14DRD4MAPK1 | |
| SCHEMBL31661929 | 0.88 | IRAK4 (0.37) | LRRK2HRH3 | |
| SCHEMBL31662279 | 0.87 | IRAK4 (0.37) | LRRK2MAPK1CHRM1 | |
| SCHEMBL31662162 | 0.87 | IRAK4 (0.37) | LRRK2MAPK1CHRM1 | |
| SCHEMBL31662135 | 0.87 | IRAK4 (0.37) | LRRK2MAPK1CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | disclosed |