Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK1 | P23458 | 3/20 | 0.43 |
| ▸ | JAK3 | P52333 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ATF4 | P18848 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31662260 | 0.83 | MAPT (0.50) | KMT2AMEN1HPGDLMNAPOLB | |
| SCHEMBL31662199 | 0.83 | JAK1 (0.40) | JAK1JAK3ROCK2 | |
| SCHEMBL31662165 | 0.82 | IRAK4 (0.37) | JAK1JAK3ROCK2 | |
| SCHEMBL31662042 | 0.82 | IRAK4 (0.41) | JAK1JAK3 | |
| SCHEMBL31662285 | 0.82 | FKBP1A (0.50) | HPGDHTTRAB9ALMNAPOLB | |
| SCHEMBL31661929 | 0.82 | IRAK4 (0.37) | JAK1JAK3ROCK2 | |
| SCHEMBL31662421 | 0.80 | MCL1 (0.44) | KMT2AMEN1PRMT5 | |
| SCHEMBL31662279 | 0.79 | IRAK4 (0.37) | JAK1JAK3ATF4ROCK2 | |
| SCHEMBL31662135 | 0.79 | IRAK4 (0.37) | JAK1JAK3ATF4ROCK2 | |
| SCHEMBL31662162 | 0.79 | IRAK4 (0.37) | JAK1JAK3ATF4ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | claimed |
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | disclosed |