Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 11/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | JAK1 | P23458 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31662179 | 0.88 | CSF1R (0.34) | DRD2 | |
| SCHEMBL31661980 | 0.87 | SCN9A (0.34) | JAK3JAK2 | |
| SCHEMBL31661973 | 0.82 | TSHR (0.37) | JAK3 | |
| SCHEMBL31661843 | 0.81 | GRM2 (0.32) | DRD2GRM2 | |
| SCHEMBL31662164 | 0.75 | SCN9A (0.32) | — | |
| SCHEMBL31662145 | 0.73 | RAB9A (0.39) | — | |
| SCHEMBL31662273 | 0.72 | MCHR2 (0.34) | DRD2 | |
| SCHEMBL31662191 | 0.71 | HRH3 (0.44) | — | |
| SCHEMBL31662137 | 0.71 | HRH2 (0.42) | — | |
| SCHEMBL31661899 | 0.68 | HRH3 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | claimed |
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | disclosed |