Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | MCHR2 | Q969V1 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31662164 | 0.93 | SCN9A (0.32) | MCHR2MCHR1 | |
| SCHEMBL31662273 | 0.92 | MCHR2 (0.34) | MCHR2MCHR1DRD2 | |
| SCHEMBL31662118 | 0.89 | CSF1R (0.35) | MCHR2MCHR1DRD2 | |
| SCHEMBL31662146 | 0.88 | MCHR2 (0.35) | MCHR2MCHR1 | |
| SCHEMBL31662111 | 0.88 | MCHR2 (0.33) | MCHR2MCHR1 | |
| SCHEMBL31661948 | 0.81 | LIPE (0.37) | — | |
| SCHEMBL31662004 | 0.81 | JAK3 (0.33) | GRM2DRD2 | |
| SCHEMBL31661994 | 0.78 | MCHR2 (0.31) | MCHR2MCHR1 | |
| SCHEMBL31662154 | 0.78 | TUBB4A (0.34) | MCHR2MCHR1 | |
| SCHEMBL31661901 | 0.75 | MCHR2 (0.32) | MCHR2MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | claimed |
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | disclosed |