Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 20/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL31662115 | 0.87 | KRAS (0.46) | KRAS | |
| SCHEMBL31526935 | 0.86 | KRAS (0.45) | KRAS | |
| SCHEMBL31662106 | 0.85 | ATR (0.32) | KRAS | |
| SCHEMBL31662196 | 0.84 | KRAS (0.44) | KRAS | |
| SCHEMBL31662121 | 0.83 | ATR (0.31) | KRAS | |
| SCHEMBL31243045 | 0.80 | KRAS (0.46) | KRAS | |
| SCHEMBL31662357 | 0.79 | KRAS (0.43) | KRAS | |
| SCHEMBL31662116 | 0.79 | KRAS (0.41) | KRAS | |
| SCHEMBL31526978 | 0.79 | KRAS (0.47) | KRAS | |
| SCHEMBL31662041 | 0.77 | KRAS (0.55) | KRAS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025151594-A1 | FUSED AZINES AS RAS INHIBITORS AND METHODS OF USE THEREOF | KESTREL THERAPEUTICS INC. (US) | 2025-07-17 | — | — | WO | disclosed |