⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25180363 | 0.82 | MAPT (0.31) | — | |
| SCHEMBL31291676 | 0.81 | GRM5 (0.35) | — | |
| SCHEMBL31618520 | 0.81 | SMN1; SMN2 (0.31) | — | |
| SCHEMBL19617225 | 0.79 | GRM5 (0.32) | — | |
| SCHEMBL30922441 | 0.79 | CA1 (0.40) | — | |
| SCHEMBL30758972 | 0.78 | — | — | |
| SCHEMBL19616761 | 0.78 | THRA (0.31) | — | |
| SCHEMBL3155327 | 0.77 | CA2 (0.40) | — | |
| SCHEMBL30758963 | 0.77 | CA2 (0.33) | — | |
| SCHEMBL23043217 | 0.76 | SOS1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250304599-A1 | MACROCYCLIC COMPOUNDS AND METHODS OF USE | AMGEN INC. (US) | 2025-10-02 | — | — | US | disclosed |
| WO-2025151594-A1 | FUSED AZINES AS RAS INHIBITORS AND METHODS OF USE THEREOF | KESTREL THERAPEUTICS INC. (US) | 2025-07-17 | — | — | WO | disclosed |