Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.46 |
| ▸ | NOS1 | P29475 | 3/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.37 |
| ▸ | WNT3A | P56704 | 1/20 | 0.37 |
| ▸ | TPMT | P51580 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | ACACA | Q13085 | 1/20 | 0.36 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.36 |
| ▸ | PLK4 | O00444 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | CSF1R | P07333 | 1/20 | 0.36 |
| ▸ | RET | P07949 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30971340 | 0.85 | MAP2K1 (0.45) | NOS1TSHRCTNNB1WNT3ADYRK1B | |
| SCHEMBL15683151 | 0.81 | KDM4E (0.44) | NOS1ALOX15TSHRPOLBACACB | |
| SCHEMBL11577272 | 0.81 | PLK4 (0.44) | ALOX15TSHRHIF1AHCAR2CTNNB1 | |
| SCHEMBL1144199 | 0.81 | CA12 (0.45) | ALOX15TSHRHIF1APOLBCTNNB1 | |
| SCHEMBL551333 | 0.79 | ACACB (0.48) | ACACBACACA | |
| SCHEMBL1144369 | 0.79 | TTR (0.46) | TTRNOS1ALOX15TSHRHIF1A | |
| SCHEMBL1145116 | 0.77 | ACACB (0.42) | ALOX15TSHRHIF1AHCAR2CTNNB1 | |
| SCHEMBL1145055 | 0.76 | CA12 (0.50) | TSHRTPMTACACBACACA | |
| SCHEMBL2672110 | 0.76 | RXRA (0.55) | ALOX15TSHRHIF1ACTNNB1WNT3A | |
| SCHEMBL11577531 | 0.74 | NOS1 (0.53) | NOS1TSHRCHEK1FGFR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | disclosed |