Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | XDH | P47989 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | FUT7 | Q11130 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31662342 | 0.98 | KDM4E (0.50) | KDM4EALDH1A1CA1CA2CA12 | |
| SCHEMBL583270 | 0.85 | KDM4E (0.64) | KDM4EALDH1A1CA1CA2CA12 | |
| SCHEMBL14150577 | 0.83 | KDM4E (0.69) | KDM4EALDH1A1CA1CA2CA12 | |
| SCHEMBL31211666 | 0.81 | KDM4E (0.50) | KDM4EALDH1A1CA1CA2CA12 | |
| SCHEMBL3512793 | 0.81 | KDM4E (0.50) | KDM4EALDH1A1CA1CA2CA12 | |
| SCHEMBL31703363 | 0.79 | KDM4E (0.46) | KDM4EALDH1A1CA1CA2CA12 | |
| SCHEMBL31703152 | 0.79 | ALDH1A1 (0.46) | KDM4EALDH1A1CA1CA2CA12 | |
| SCHEMBL31662526 | 0.78 | ALOX15 (0.41) | KDM4EALDH1A1CA1CA2CA12 | |
| SCHEMBL14150731 | 0.77 | KDM4E (0.44) | KDM4EALDH1A1CA1CA2CA12 | |
| SCHEMBL12837985 | 0.76 | KDM4E (0.58) | KDM4EALDH1A1CA1CA2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | disclosed |