Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1H | O95180 | 9/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.40 |
| ▸ | PLK4 | O00444 | 1/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
| ▸ | RET | P07949 | 1/20 | 0.39 |
| ▸ | MET | P08581 | 1/20 | 0.39 |
| ▸ | AXL | P30530 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
| ▸ | MST1R | Q04912 | 1/20 | 0.39 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.39 |
| ▸ | MERTK | Q12866 | 1/20 | 0.39 |
| ▸ | CAMK4 | Q16566 | 1/20 | 0.39 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.39 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.39 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31662520 | 0.88 | AR (0.40) | CACNA1HSCN9AMAPK14PLK4NTRK1 | |
| SCHEMBL31662194 | 0.84 | SCN9A (0.43) | CACNA1HSCN9APDE1CEGFRCA12 | |
| SCHEMBL31662264 | 0.83 | SCN9A (0.40) | CACNA1HSCN9AMAPK14PDE1CPLK4 | |
| SCHEMBL31662265 | 0.83 | SCN9A (0.40) | CACNA1HSCN9AMAPK14PDE1CPLK4 | |
| SCHEMBL31662635 | 0.82 | SCN9A (0.48) | CACNA1HSCN9APDE1CMAOBCA12 | |
| SCHEMBL27273910 | 0.78 | PDE1C (0.46) | CACNA1HSCN9APDE1CMAOBMAOA | |
| SCHEMBL31169517 | 0.78 | PDE1C (0.46) | CACNA1HSCN9APDE1CMAOBMAOA | |
| SCHEMBL31662084 | 0.78 | MAOB (0.36) | CACNA1HMAOBCA12CA1CA2 | |
| SCHEMBL31662169 | 0.78 | SCN9A (0.44) | CACNA1HSCN9APDE1CMAOB | |
| SCHEMBL31662415 | 0.76 | SCN9A (0.46) | CACNA1HSCN9APDE1CMAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | disclosed |