Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA7 | P43166 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31662288 | 0.88 | AR (0.40) | MAOBBRD4MAOA | |
| SCHEMBL31662433 | 0.87 | GLA (0.38) | MAOBKDM4ECYP3A4CA12CA1 | |
| SCHEMBL31662519 | 0.84 | CA12 (0.41) | KDM4ECYP3A4PTPN11CA12CA1 | |
| SCHEMBL31662347 | 0.82 | LMNA (0.38) | MAOBKDM4EPOLBCYP11B1CYP11B2 | |
| SCHEMBL31662618 | 0.78 | CACNA1H (0.41) | MAOBCA12CA1CA2CA7 | |
| SCHEMBL31662290 | 0.76 | USP2 (0.39) | KDM4EPTPN11USP2LMNAHTR2A | |
| SCHEMBL31662404 | 0.75 | SCN9A (0.40) | MAOBKDM4EPTPN11CA12CA1 | |
| SCHEMBL29046616 | 0.74 | KDM4E (0.50) | KDM4EPOLBCYP11B1CYP11B2PTPN11 | |
| SCHEMBL31662262 | 0.73 | LMNA (0.46) | MAOBPOLBUSP2LMNACYP2C19 | |
| SCHEMBL31662294 | 0.72 | HAO1 (0.39) | KDM4ECA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | disclosed |