Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | CACNA1H | O95180 | 4/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | PLK4 | O00444 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.36 |
| ▸ | RET | P07949 | 1/20 | 0.36 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
| ▸ | AXL | P30530 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
| ▸ | MST1R | Q04912 | 1/20 | 0.36 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.36 |
| ▸ | MERTK | Q12866 | 1/20 | 0.36 |
| ▸ | CAMK4 | Q16566 | 1/20 | 0.36 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.36 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.36 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.36 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31662264 | 1.00 | SCN9A (0.40) | SCN9ACACNA1HMAPK14PLK4NTRK1 | |
| SCHEMBL31662159 | 0.84 | SCN9A (0.38) | SCN9ACACNA1HMAPK14PLK4NTRK1 | |
| SCHEMBL31662618 | 0.83 | CACNA1H (0.41) | SCN9ACACNA1HMAPK14PLK4NTRK1 | |
| SCHEMBL31662477 | 0.83 | PRKAB2 (0.39) | SCN9APLK4NTRK1RETMET | |
| SCHEMBL31662635 | 0.80 | SCN9A (0.48) | SCN9ACACNA1HPDE1CMAOBMAOA | |
| SCHEMBL31662426 | 0.79 | CYP4A11 (0.44) | SCN9ACACNA1HPDE1CNOTUM | |
| SCHEMBL31662441 | 0.79 | SCN9A (0.37) | SCN9AMAPK14PLK4NTRK1RET | |
| SCHEMBL31662169 | 0.79 | SCN9A (0.44) | SCN9ACACNA1HPDE1CMAOBNOTUM | |
| SCHEMBL31662194 | 0.76 | SCN9A (0.43) | SCN9ACACNA1HPDE1CMAOANOTUM | |
| SCHEMBL31662415 | 0.75 | SCN9A (0.46) | SCN9ACACNA1HPDE1CMAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | disclosed |