Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.36 |
| ▸ | KCNAB1 | Q14722 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | KIT | P10721 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31662443 | 0.92 | ESR2 (0.44) | ESR2HTR6NR1H2PDE4APDE4B | |
| SCHEMBL30280405 | 0.79 | ESR2 (0.44) | ESR2HTR6NR1H2MMP13KCNA1 | |
| SCHEMBL31662571 | 0.77 | CD274 (0.39) | HTR6PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL31662438 | 0.76 | CD274 (0.41) | HTR6PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL31662624 | 0.72 | ESR2 (0.51) | ESR2NR1H2NAMPTGPR119MAPT | |
| SCHEMBL2056208 | 0.71 | ESR2 (0.76) | ESR2NR1H2NAMPTGPR119MAPT | |
| SCHEMBL31662706 | 0.71 | ESR2 (0.53) | ESR2NR1H2NAMPTMAPT | |
| SCHEMBL25404045 | 0.70 | ESR2 (0.66) | ESR2NR1H2NAMPTGPR119MAPT | |
| SCHEMBL31083726 | 0.70 | ESR2 (0.66) | ESR2NR1H2NAMPTGPR119MAPT | |
| SCHEMBL4789776 | 0.70 | ESR2 (0.69) | ESR2NR1H2GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025151449-A1 | BIFUNCTIONAL P53-BINDING COMPOUNDS AND USES THEREOF | PHOTYS THERAPEUTICS, INC. (US) | 2025-07-17 | — | — | WO | disclosed |