Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.53 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.47 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 2/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.41 |
| ▸ | JAK1 | P23458 | 3/20 | 0.40 |
| ▸ | CLK2 | P49760 | 2/20 | 0.39 |
| ▸ | CLK3 | P49761 | 2/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | HPGDS | O60760 | 1/20 | 0.38 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31662722 | 0.85 | ESR2 (0.52) | ESR2NR1H2MAPK1NAMPTROCK2 | |
| SCHEMBL31662624 | 0.83 | ESR2 (0.51) | ESR2NR1H2MAPK1NAMPTROCK2 | |
| SCHEMBL24804179 | 0.77 | ESR2 (0.53) | ESR2NR1H2JAK1 | |
| SCHEMBL25404045 | 0.76 | ESR2 (0.66) | ESR2NR1H2MAPK1NAMPTROCK2 | |
| SCHEMBL31083726 | 0.76 | ESR2 (0.66) | ESR2NR1H2MAPK1NAMPTROCK2 | |
| SCHEMBL15778686 | 0.76 | ESR2 (0.54) | ESR2NR1H2PIK3C3DYRK1AJAK1 | |
| SCHEMBL25404096 | 0.75 | ESR2 (0.61) | ESR2NR1H2 | |
| SCHEMBL31083736 | 0.75 | ESR2 (0.61) | ESR2NR1H2 | |
| SCHEMBL25407478 | 0.74 | ESR2 (0.60) | ESR2NR1H2BRD4MAPK1NAMPT | |
| SCHEMBL30593261 | 0.74 | ESR2 (0.60) | ESR2NR1H2BRD4MAPK1NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025151449-A1 | BIFUNCTIONAL P53-BINDING COMPOUNDS AND USES THEREOF | PHOTYS THERAPEUTICS, INC. (US) | 2025-07-17 | — | — | WO | disclosed |