Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.40 |
| ▸ | KCNA1 | Q09470 | 3/20 | 0.37 |
| ▸ | KCNAB1 | Q14722 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | KIT | P10721 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK3 | P52333 | 1/20 | 0.35 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 2/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31662630 | 0.92 | ESR2 (0.46) | ESR2HTR6NR1H2KCNA1KCNAB1 | |
| SCHEMBL30280405 | 0.78 | ESR2 (0.44) | ESR2HTR6NR1H2KCNA1KCNAB1 | |
| SCHEMBL25304050 | 0.77 | HTR6 (0.39) | ESR2HTR6NR1H2MMP13GPR119 | |
| SCHEMBL30381434 | 0.77 | HTR6 (0.39) | ESR2HTR6NR1H2MMP13GPR119 | |
| SCHEMBL31662624 | 0.76 | ESR2 (0.51) | ESR2NR1H2JAK2JAK3PTK2 | |
| SCHEMBL21593085 | 0.75 | MAPT (0.37) | ESR2HTR6NR1H2ALDH1A1HPGD | |
| SCHEMBL15778729 | 0.74 | BRD4 (0.47) | ESR2HTR6NR1H2JAK2JAK3 | |
| SCHEMBL21593084 | 0.74 | NR1H2 (0.42) | ESR2HTR6NR1H2ALDH1A1HPGD | |
| SCHEMBL21593086 | 0.74 | NR1H2 (0.44) | ESR2HTR6NR1H2ALDH1A1HPGD | |
| SCHEMBL31662722 | 0.72 | ESR2 (0.52) | ESR2NR1H2JAK2JAK3PTK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025151449-A1 | BIFUNCTIONAL P53-BINDING COMPOUNDS AND USES THEREOF | PHOTYS THERAPEUTICS, INC. (US) | 2025-07-17 | — | — | WO | disclosed |