Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 3/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.40 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.40 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.40 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29284943 | 0.89 | CTSL (0.47) | CTSLCTSBCTSKOPRM1OPRL1 | |
| SCHEMBL31248144 | 0.87 | OPRM1 (0.51) | CTSLCTSBCTSKOPRM1OPRL1 | |
| SCHEMBL21028919 | 0.84 | CTSL (0.47) | CTSLCTSBCTSKOPRM1OPRL1 | |
| SCHEMBL29079652 | 0.81 | SLC6A2 (0.52) | CTSLCTSBCTSKOPRM1OPRL1 | |
| SCHEMBL21673506 | 0.81 | SLC6A2 (0.52) | CTSLCTSBCTSKOPRM1OPRL1 | |
| SCHEMBL28179070 | 0.81 | OPRM1 (0.47) | CTSLCTSBCTSKOPRM1OPRL1 | |
| SCHEMBL28072324 | 0.80 | CTSL (0.46) | CTSLCTSBCTSKOPRM1OPRL1 | |
| SCHEMBL11244939 | 0.80 | CTSL (0.46) | CTSLCTSBCTSKOPRM1OPRL1 | |
| SCHEMBL22901710 | 0.76 | CTSL (0.49) | CTSLCTSBCTSKOPRM1OPRL1 | |
| SCHEMBL1560105 | 0.76 | CTSL (0.43) | CTSLCTSBCTSKOPRM1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | disclosed |