Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.52 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.46 |
| ▸ | F12 | P00748 | 3/20 | 0.37 |
| ▸ | NAMPT | P43490 | 2/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | CDK9 | P50750 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | HPGDS | O60760 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK3 | P52333 | 1/20 | 0.35 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31662706 | 0.85 | ESR2 (0.53) | ESR2NR1H2NAMPTROCK2MAPK1 | |
| SCHEMBL31662624 | 0.83 | ESR2 (0.51) | ESR2NR1H2NAMPTROCK2MAPK1 | |
| SCHEMBL25404045 | 0.75 | ESR2 (0.66) | ESR2NR1H2NAMPTROCK2MAPK1 | |
| SCHEMBL31083726 | 0.75 | ESR2 (0.66) | ESR2NR1H2NAMPTROCK2MAPK1 | |
| SCHEMBL25404096 | 0.74 | ESR2 (0.61) | ESR2NR1H2GPR119CYP11B1CYP11B2 | |
| SCHEMBL31083736 | 0.74 | ESR2 (0.61) | ESR2NR1H2GPR119CYP11B1CYP11B2 | |
| SCHEMBL1365225 | 0.73 | ESR2 (0.74) | ESR2NR1H2NAMPTMAPK1MAPT | |
| SCHEMBL25407478 | 0.73 | ESR2 (0.60) | ESR2NR1H2NAMPTMAPK1MAPT | |
| SCHEMBL30593261 | 0.73 | ESR2 (0.60) | ESR2NR1H2NAMPTMAPK1MAPT | |
| SCHEMBL15779488 | 0.73 | PAK1 (0.53) | ESR2NR1H2NAMPTROCK2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025151449-A1 | BIFUNCTIONAL P53-BINDING COMPOUNDS AND USES THEREOF | PHOTYS THERAPEUTICS, INC. (US) | 2025-07-17 | — | — | WO | disclosed |