Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 2/20 | 0.49 |
| ▸ | JAK2 | O60674 | 6/20 | 0.47 |
| ▸ | JAK1 | P23458 | 1/20 | 0.47 |
| ▸ | JAK3 | P52333 | 1/20 | 0.47 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.46 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.46 |
| ▸ | MET | P08581 | 2/20 | 0.44 |
| ▸ | FLT3 | P36888 | 1/20 | 0.44 |
| ▸ | SYK | P43405 | 1/20 | 0.44 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.44 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.43 |
| ▸ | MAP3K12 | Q12852 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | CSF1R | P07333 | 1/20 | 0.41 |
| ▸ | LYN | P07948 | 1/20 | 0.41 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.41 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.41 |
| ▸ | SIK1 | P57059 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31662800 | 0.83 | KCNH2 (0.43) | DYRK1AKCNH2PIK3CDPIK3CAPIK3CB | |
| SCHEMBL22466195 | 0.74 | ERN1 (0.65) | PRKAB2ABL1CSF1RLYNTGFBR1 | |
| SCHEMBL31662834 | 0.72 | DRD1 (0.41) | KCNH2 | |
| SCHEMBL31662997 | 0.72 | POLB (0.39) | KCNH2 | |
| SCHEMBL22431103 | 0.71 | TTK (0.54) | JAK2JAK1JAK3MKNK1MKNK2 | |
| SCHEMBL18149618 | 0.70 | DYRK1A (0.44) | DYRK1AJAK2JAK1JAK3MKNK1 | |
| SCHEMBL24956536 | 0.70 | MET (0.49) | DYRK1AJAK2JAK1JAK3MKNK1 | |
| SCHEMBL31663033 | 0.69 | KCNH2 (0.55) | KCNH2 | |
| SCHEMBL24532595 | 0.68 | ALK (0.56) | DYRK1AMKNK1METALKKCNH2 | |
| SCHEMBL28060611 | 0.67 | DRD1 (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149498-A1 | BENZYLPIPERIDINE DERIVATIVES AS TRP4 ANTAGONISTS FOR THE TREATMENT OF INFLAMMATORY DISEASES | ASTRAZENECA AB (SE) | 2025-07-17 | — | — | WO | disclosed |