SCHEMBL31663033

SCHEMBL31663033

O=Cc1ccc(-c2cnn(CCc3ccccc3)c2)cc1OC(F)F

nearest known ligand 0.55

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 20/20 0.55
GRIN2B Q13224 9/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28060611 0.75 DRD1 (0.51)
SCHEMBL31662800 0.75 KCNH2 (0.43) KCNH2GRIN2B
SCHEMBL31662834 0.72 DRD1 (0.41) KCNH2GRIN2B
SCHEMBL31662997 0.72 POLB (0.39) KCNH2GRIN2B
SCHEMBL17493828 0.71 KCNH2 (1.00) KCNH2GRIN2B
SCHEMBL30364077 0.71 KCNH2 (1.00) KCNH2GRIN2B
SCHEMBL30364096 0.71 KCNH2 (1.00) KCNH2GRIN2B
SCHEMBL17493943 0.71 KCNH2 (1.00) KCNH2GRIN2B
SCHEMBL31662933 0.69 HPGDS (0.45) GRIN2B
SCHEMBL31662797 0.69 DYRK1A (0.49) KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025149498-A1 BENZYLPIPERIDINE DERIVATIVES AS TRP4 ANTAGONISTS FOR THE TREATMENT OF INFLAMMATORY DISEASES ASTRAZENECA AB (SE) 2025-07-17 WO disclosed