Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 2/20 | 0.37 |
| ▸ | PSEN1 | P49768 | 7/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 7/20 | 0.36 |
| ▸ | APH1B | Q8WW43 | 7/20 | 0.36 |
| ▸ | NCSTN | Q92542 | 7/20 | 0.36 |
| ▸ | APH1A | Q96BI3 | 7/20 | 0.36 |
| ▸ | PSENEN | Q9NZ42 | 7/20 | 0.36 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 2/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31663148 | 0.83 | NPC1 (0.47) | DRD1MAP4K4NPC1RAB9ANLRP3 | |
| SCHEMBL31662976 | 0.80 | POLB (0.39) | DRD1FLT3POLBGRIN2BPDE4A | |
| SCHEMBL31662997 | 0.77 | POLB (0.39) | POLBGRIN2BKCNH2 | |
| SCHEMBL15034498 | 0.74 | NPC1 (0.57) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL16793341 | 0.72 | DRD1 (0.42) | DRD1LMNAHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL19244917 | 0.72 | NPC1 (0.42) | MAP4K4NPC1RAB9ANLRP3 | |
| SCHEMBL1230371 | 0.70 | MAOA (0.42) | MAP4K4NPC1RAB9ANLRP3MAPK1 | |
| SCHEMBL31663008 | 0.70 | DRD1 (0.41) | DRD1NLRP3PDE4APDE4BPDE4C | |
| SCHEMBL31662983 | 0.70 | PDE4A (0.45) | DRD1POLBGRIN2BPDE4APDE4B | |
| SCHEMBL31662834 | 0.68 | DRD1 (0.41) | DRD1GRIN2BKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149498-A1 | BENZYLPIPERIDINE DERIVATIVES AS TRP4 ANTAGONISTS FOR THE TREATMENT OF INFLAMMATORY DISEASES | ASTRAZENECA AB (SE) | 2025-07-17 | — | — | WO | disclosed |