Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.34 |
| ▸ | USP1 | O94782 | 2/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.33 |
| ▸ | SCN4A | P35499 | 2/20 | 0.33 |
| ▸ | PDE4A | P27815 | 2/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31663008 | 0.91 | DRD1 (0.41) | DRD1KMT2APDE4DPDE4APDE4B | |
| SCHEMBL31663007 | 0.88 | MEN1 (0.42) | DRD1KMT2AKDM4EPTGS2PDE4D | |
| SCHEMBL31663136 | 0.84 | PDE4D (0.35) | PDE4DPDE4APDE4BPDE4CPDE3B | |
| SCHEMBL31662978 | 0.80 | DRD1 (0.36) | DRD1KMT2AKDM4EPDE4DPDE4A | |
| SCHEMBL31662997 | 0.80 | POLB (0.39) | POLBGRIN1GRIN2B | |
| SCHEMBL31662953 | 0.80 | DRD1 (0.37) | POLBFLT3DRD1PDE4DPDE4A | |
| SCHEMBL31662974 | 0.75 | CRHR1 (0.39) | PDE4DPDE4APDE4BPDE4CPDE3B | |
| SCHEMBL16793341 | 0.72 | DRD1 (0.42) | DRD1KMT2AKDM4EL3MBTL1LMNA | |
| SCHEMBL31662955 | 0.72 | SMN1; SMN2 (0.38) | POLBDRD1KMT2AKDM4EL3MBTL1 | |
| SCHEMBL31662834 | 0.70 | DRD1 (0.41) | DRD1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149498-A1 | BENZYLPIPERIDINE DERIVATIVES AS TRP4 ANTAGONISTS FOR THE TREATMENT OF INFLAMMATORY DISEASES | ASTRAZENECA AB (SE) | 2025-07-17 | — | — | WO | disclosed |