Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.45 |
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.39 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | SLC10A2 | Q12908 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31406453 | 0.82 | CA12 (0.55) | CA12CA1CA9DGAT1SIRT2 | |
| SCHEMBL17920282 | 0.82 | DGAT1 (0.47) | CA12CA1CA9DGAT1SIRT2 | |
| SCHEMBL5891978 | 0.80 | CA12 (0.49) | CA12CA1CA9MAP4K4CYP17A1 | |
| SCHEMBL25894545 | 0.80 | DGAT1 (0.45) | CA12CA1CA9DGAT1SIRT2 | |
| SCHEMBL23298925 | 0.79 | SIRT2 (0.48) | CA12CA1CA9DGAT1SIRT2 | |
| SCHEMBL13014981 | 0.79 | CA12 (0.46) | CA12CA1CA9DGAT1SIRT2 | |
| SCHEMBL29880812 | 0.79 | SIRT2 (0.48) | CA12CA1CA9DGAT1SIRT2 | |
| SCHEMBL29955042 | 0.79 | CA12 (0.48) | CA12CA1CA9MAP4K4CYP17A1 | |
| SCHEMBL31662881 | 0.79 | CA12 (0.48) | CA12CA1CA9MAP4K4CYP17A1 | |
| SCHEMBL29956706 | 0.79 | CA12 (0.48) | CA12CA1CA9MAP4K4CYP17A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149498-A1 | BENZYLPIPERIDINE DERIVATIVES AS TRP4 ANTAGONISTS FOR THE TREATMENT OF INFLAMMATORY DISEASES | ASTRAZENECA AB (SE) | 2025-07-17 | — | — | WO | disclosed |