Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 10/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | GRM5 | P41594 | 2/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.32 |
| ▸ | PDE4A | P27815 | 2/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.30 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.30 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.30 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31662978 | 0.84 | DRD1 (0.36) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL31663309 | 0.84 | GRIN2B (0.36) | KCNH2GRM5CYP11B1CYP11B2GRIN1 | |
| SCHEMBL31663302 | 0.76 | PHGDH (0.34) | GRIN1GRIN2BPDE4APDE4BPDE4C | |
| SCHEMBL31663325 | 0.76 | PTGS2 (0.37) | KCNH2GRIN1GRIN2BLMNACYP1A2 | |
| SCHEMBL31662976 | 0.75 | POLB (0.39) | GRIN1GRIN2BPDE4APDE4BPDE4C | |
| SCHEMBL31663008 | 0.75 | DRD1 (0.41) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL31663007 | 0.75 | MEN1 (0.42) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL31663136 | 0.71 | PDE4D (0.35) | GRIN1GRIN2BPDE4APDE4BPDE4C | |
| SCHEMBL31662955 | 0.68 | SMN1; SMN2 (0.38) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL31662923 | 0.67 | PDE4A (0.48) | KCNH2GRIN2BPDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149498-A1 | BENZYLPIPERIDINE DERIVATIVES AS TRP4 ANTAGONISTS FOR THE TREATMENT OF INFLAMMATORY DISEASES | ASTRAZENECA AB (SE) | 2025-07-17 | — | — | WO | disclosed |