Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CDK8 | P49336 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31663120 | 0.77 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2HSD17B10HPGDUSP2 | |
| SCHEMBL12647214 | 0.76 | KDM4E (0.49) | ALDH1A1SMN1; SMN2HSD17B10HPGDNPC1 | |
| SCHEMBL4119504 | 0.74 | RAB9A (0.63) | ALDH1A1SMN1; SMN2HSD17B10NPC1MAPT | |
| SCHEMBL31618800 | 0.70 | CYP1A2 (0.52) | ALDH1A1SMN1; SMN2HSD17B10HPGDNPC1 | |
| SCHEMBL11492277 | 0.70 | TSHR (0.52) | ALDH1A1SMN1; SMN2HSD17B10PKMHPGD | |
| SCHEMBL848310 | 0.69 | SMN1; SMN2 (0.37) | SMN1; SMN2RAB9AKDM4ERXFP1 | |
| SCHEMBL15979055 | 0.69 | SMN1; SMN2 (0.44) | ALDH1A1SMN1; SMN2HSD17B10PKMHPGD | |
| SCHEMBL31663123 | 0.69 | SMN1; SMN2 (0.51) | ALDH1A1SMN1; SMN2HSD17B10HPGDUSP2 | |
| SCHEMBL31663160 | 0.69 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2HSD17B10HPGDUSP2 | |
| SCHEMBL28354652 | 0.68 | SMN1; SMN2 (0.47) | ALDH1A1SMN1; SMN2HPGDNPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149628-A1 | PIPERIDINE DERIVATIVES AS INHIBITORS OF NICOTINAMIDE N-METHYL TRANSFERASE | ASTRAZENECA AB (SE) | 2025-07-17 | — | — | WO | disclosed |