Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.51 |
| ▸ | STS | P08842 | 5/20 | 0.50 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | GCK | P35557 | 1/20 | 0.46 |
| ▸ | DTYMK | P23919 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | PTPRB | P23467 | 1/20 | 0.44 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31663026 | 1.00 | POLB (0.52) | POLBGPR119STSPTPN2PTPN1 | |
| SCHEMBL31663264 | 0.86 | PTPN2 (0.49) | GPR119STSPTPN2PTPN1PTPN6 | |
| SCHEMBL1137790 | 0.84 | GPR119 (0.57) | POLBGPR119STSPTPN2PTPN1 | |
| SCHEMBL31663119 | 0.81 | GPR119 (0.50) | GPR119STSPTPN2PTPN1PTPN6 | |
| SCHEMBL31663064 | 0.80 | GPR119 (0.57) | GPR119STSPTPN2PTPN1PTPN6 | |
| SCHEMBL1653114 | 0.79 | KDM4E (0.62) | GPR119STSPTPN2PTPN1PTPN6 | |
| SCHEMBL20135438 | 0.79 | KMT2A (0.54) | GPR119STSPTPN2PTPN1PTPN6 | |
| SCHEMBL12833233 | 0.79 | POLB (0.75) | POLBGPR119KMT2ADTYMKMEN1 | |
| SCHEMBL14359553 | 0.77 | PTPN2 (0.52) | GPR119STSPTPN2PTPN1PTPN6 | |
| SCHEMBL21921216 | 0.76 | POLB (0.55) | POLBGPR119STSPTPN2PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149628-A1 | PIPERIDINE DERIVATIVES AS INHIBITORS OF NICOTINAMIDE N-METHYL TRANSFERASE | ASTRAZENECA AB (SE) | 2025-07-17 | — | — | WO | disclosed |