SCHEMBL31663032

SCHEMBL31663032

Cc1nc(CN2CCC(C#CC(=O)C3=CNN4C=COC=C34)CC2)nc2ccccc12

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
OGA O60502 2/20 0.33
ALDH1A1 P00352 2/20 0.32
ACHE P22303 3/20 0.32
BCHE P06276 2/20 0.32
LMNA P02545 1/20 0.31
TP53 P04637 1/20 0.31
HTT P42858 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
DPP4 P27487 10/20 0.31
FAP Q12884 4/20 0.31
CHRM1 P11229 2/20 0.30
POU2F2 P09086 1/20 0.30
ADORA3 P0DMS8 1/20 0.30
POU2F1 P14859 1/20 0.30
CHRM3 P20309 1/20 0.30
HRH2 P25021 1/20 0.30
MC4R P32245 1/20 0.30
DPP8 Q6V1X1 1/20 0.30
DPP9 Q86TI2 1/20 0.30
GHSR Q92847 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31663300 0.76 OGA (0.34) OGAACHEBCHEDPP4FAP
SCHEMBL31663327 0.75 CYP2C9 (0.41) OGAALDH1A1LMNASMN1; SMN2
SCHEMBL31663115 0.75 OGA (0.36) OGAALDH1A1LMNASMN1; SMN2DPP4
SCHEMBL31662944 0.74 OGA (0.37) OGAALDH1A1ACHEBCHEHTT
SCHEMBL31663181 0.71 OGA (0.36) OGAALDH1A1ACHELMNASMN1; SMN2
SCHEMBL31663276 0.71 MGLL (0.36) OGAALDH1A1DPP4FAPCHRM1
SCHEMBL31663067 0.70 DPP4 (0.37) OGADPP4FAPCHRM1POU2F2
SCHEMBL31662940 0.68 DPP4 (0.40) ALDH1A1ACHELMNAHTTDPP4
SCHEMBL31663310 0.67 MAPT (0.43) ALDH1A1ACHELMNAHTT
SCHEMBL31663114 0.60

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025149628-A1 PIPERIDINE DERIVATIVES AS INHIBITORS OF NICOTINAMIDE N-METHYL TRANSFERASE ASTRAZENECA AB (SE) 2025-07-17 WO disclosed