SCHEMBL31663310

SCHEMBL31663310

Cc1nc(CN2CCC(O)CC2)nc2ccccc12

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.43
LTA4H P09960 1/20 0.43
DRD2 P14416 3/20 0.42
DRD4 P21917 3/20 0.42
DRD3 P35462 3/20 0.42
GRM2 Q14416 1/20 0.42
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42
KCNA3 P22001 1/20 0.41
PDE10A Q9Y233 2/20 0.41
PDE2A O00408 1/20 0.41
ALDH1A1 P00352 1/20 0.41
CYP1A2 P05177 1/20 0.41
HPGD P15428 1/20 0.41
NUDT1 P36639 1/20 0.41
HSD17B10 Q99714 1/20 0.41
NCF1 P14598 1/20 0.40
GPR3 P46089 1/20 0.40
ACHE P22303 1/20 0.40
LMNA P02545 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31662619 0.84 ALDH1A1 (0.57) MAPTLTA4HNPC1PDE10APDE2A
SCHEMBL31662940 0.83 DPP4 (0.40) MAPTDRD2DRD4DRD3GRM2
SCHEMBL31662766 0.80 TUBB4A (0.36) MAPTDRD2DRD4DRD3GRM2
SCHEMBL31663271 0.80 DPP4 (0.41)
SCHEMBL31663067 0.78 DPP4 (0.37) DRD2DRD4DRD3GRM2
SCHEMBL17433855 0.74 MAPT (0.45) MAPTLTA4HNPC1RAB9AKCNA3
SCHEMBL31663193 0.73 DRD2 (0.50) DRD2DRD4DRD3ALDH1A1HPGD
SCHEMBL31663078 0.73 GPR119 (0.43) MAPTLMNA
SCHEMBL31663327 0.73 CYP2C9 (0.41) RAB9AALDH1A1CYP1A2HPGDHSD17B10
SCHEMBL16432784 0.72 GPR3 (0.53) NPC1RAB9APDE10AALDH1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025149628-A1 PIPERIDINE DERIVATIVES AS INHIBITORS OF NICOTINAMIDE N-METHYL TRANSFERASE ASTRAZENECA AB (SE) 2025-07-17 WO disclosed