Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 5/20 | 0.42 |
| ▸ | STS | P08842 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GBA1 | P04062 | 1/20 | 0.41 |
| ▸ | NSD2 | O96028 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31662940 | 0.85 | DPP4 (0.40) | MAPTCHRM1CHRM3LMNA | |
| SCHEMBL30958238 | 0.77 | CHRM2 (0.52) | GPR119MAPTKDM4EGAAGBA1 | |
| SCHEMBL427670 | 0.73 | HPGD (0.58) | GPR119STSMAPTKDM4ETHRB | |
| SCHEMBL25523742 | 0.73 | GPR119 (0.50) | GPR119MAPTKDM4EPKMTHRB | |
| SCHEMBL31663310 | 0.73 | MAPT (0.43) | MAPTLMNA | |
| SCHEMBL13793840 | 0.72 | KDM4E (0.58) | GPR119KDM4EPKMTHRBGAA | |
| SCHEMBL31663067 | 0.72 | DPP4 (0.37) | CHRM1CHRM3 | |
| SCHEMBL31663271 | 0.71 | DPP4 (0.41) | CHRM1CHRM3 | |
| SCHEMBL22565170 | 0.71 | HPGD (0.47) | GPR119MAPTKDM4EPKMSMN1; SMN2 | |
| SCHEMBL30735960 | 0.70 | KDM4E (0.48) | GPR119MAPTKDM4EPKMTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149628-A1 | PIPERIDINE DERIVATIVES AS INHIBITORS OF NICOTINAMIDE N-METHYL TRANSFERASE | ASTRAZENECA AB (SE) | 2025-07-17 | — | — | WO | disclosed |