Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PRKCA | P17252 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3873477 | 0.84 | LMNA (0.34) | LMNACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL14831429 | 0.82 | LMNA (0.33) | LMNACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL14831431 | 0.82 | LMNA (0.33) | LMNACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL27328480 | 0.77 | LMNA (0.42) | LMNACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL3166310 | 0.77 | LMNA (0.38) | LMNACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL1487050 | 0.77 | LMNA (0.38) | LMNACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL14598126 | 0.77 | LMNA (0.33) | LMNACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL3166174 | 0.77 | LMNA (0.38) | LMNACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL18341170 | 0.74 | — | — | |
| SCHEMBL18625594 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2150269-A1 | NEW CYCLIC PEPTIDE COMPOUNDS | Astellas Pharma Inc. (JP) | 2010-02-10 | — | — | EP | disclosed |
| WO-2008139986-A1 | NEW CYCLIC PEPTIDE COMPOUNDS | ASTELLAS PHARMA INC., (JP) | 2008-11-20 | — | — | WO | disclosed |