SCHEMBL3873477

SCHEMBL3873477

CC(C)(C)C(OC(N)=O)C(O)CN

nearest known ligand 0.34

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.34
CHRM2 P08172 1/20 0.34
CHRM4 P08173 1/20 0.34
CHRM5 P08912 1/20 0.34
CHRM1 P11229 1/20 0.34
CHRM3 P20309 1/20 0.34
CYP2C9 P11712 1/20 0.34
TSHR P16473 1/20 0.34
MAPT P10636 1/20 0.33
HSD17B10 Q99714 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3166354 0.84 LMNA (0.34) LMNACHRM2CHRM4CHRM5CHRM1
SCHEMBL14831429 0.82 LMNA (0.33) LMNACHRM2CHRM4CHRM5CHRM1
SCHEMBL14831431 0.82 LMNA (0.33) LMNACHRM2CHRM4CHRM5CHRM1
SCHEMBL28630324 0.77 LMNA (0.42) LMNACHRM2CHRM4CHRM5CHRM1
SCHEMBL14598126 0.77 LMNA (0.33) LMNACHRM2CHRM4CHRM5CHRM1
SCHEMBL3166310 0.77 LMNA (0.38) LMNACHRM2CHRM4CHRM5CHRM1
SCHEMBL28630322 0.77 LMNA (0.42) LMNACHRM2CHRM4CHRM5CHRM1
SCHEMBL1487050 0.77 LMNA (0.38) LMNACHRM2CHRM4CHRM5CHRM1
SCHEMBL3166174 0.77 LMNA (0.38) LMNACHRM2CHRM4CHRM5CHRM1
SCHEMBL3341773 0.74 LMNA (0.34) LMNACHRM2CHRM4CHRM5CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8076466-B2 Saccharidic fluorescent substrates, their process of preparation and their use COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) 2011-12-13 US disclosed
US-20090081634-A1 FLUORESCENT AND SACCHARIDIC SUBSTRATES, THEIR PROCESS OF PREPARATION AND THEIR USE COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) 2009-03-26 US disclosed
EP-2033663-A1 Saccharidic fluorescent substrates, method of preparing same and use of same Commissariat à l'Energie Atomique (FR) 2009-03-11 EP disclosed