Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.43 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.43 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.43 |
| ▸ | KMO | O15229 | 1/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30373962 | 0.91 | LTA4H (0.50) | SMN1; SMN2KDM4EALDH1A1KMT2AMAPT | |
| SCHEMBL26089876 | 0.91 | LTA4H (0.50) | SMN1; SMN2KDM4EALDH1A1KMT2AMAPT | |
| Hydrochloric Acid SCHEMBL30373901 | 0.90 | LTA4H (0.49) | SMN1; SMN2KDM4EALDH1A1KMT2AMAPT | |
| Hydrochloric Acid SCHEMBL26090978 | 0.90 | LTA4H (0.49) | SMN1; SMN2KDM4EALDH1A1KMT2AMAPT | |
| SCHEMBL29619013 | 0.87 | BRD4 (0.48) | SMN1; SMN2KDM4ENPC1ALDH1A1RAB9A | |
| SCHEMBL1166226 | 0.82 | HTR2A (0.60) | HTR2AHTR2C | |
| SCHEMBL3214392 | 0.80 | NPC1 (0.55) | SMN1; SMN2KDM4ENPC1ALDH1A1RAB9A | |
| SCHEMBL3940129 | 0.79 | KMT2A (0.61) | SMN1; SMN2KDM4ENPC1ALDH1A1RAB9A | |
| SCHEMBL2086647 | 0.79 | KMT2A (0.61) | SMN1; SMN2KDM4ENPC1ALDH1A1RAB9A | |
| SCHEMBL29619010 | 0.79 | MAPT (0.46) | SMN1; SMN2KDM4EALDH1A1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4236937-B1 | PYRIMIDINE DERIVATIVES AS MODULATORS OF THE 5-HT2A SEROTONIN RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO | ARENA PHARM INC (US) | 2025-07-23 | — | — | EP | disclosed |