Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 5/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.39 |
| ▸ | OXTR | P30559 | 1/20 | 0.39 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16823475 | 1.00 | CYP11B2 (0.45) | CYP11B2HSD17B10GAASMN1; SMN2POLB | |
| SCHEMBL31016655 | 0.90 | AKT1 (0.43) | CYP11B2HSD17B10SMN1; SMN2POLBNOTUM | |
| SCHEMBL31492896 | 0.86 | GAA (0.43) | HSD17B10GAASMN1; SMN2POLBPTPN11 | |
| SCHEMBL14970381 | 0.84 | NOTUM (0.58) | CYP11B2GAASMN1; SMN2NOTUMMEN1 | |
| SCHEMBL30158322 | 0.84 | NOTUM (0.58) | CYP11B2GAASMN1; SMN2NOTUMMEN1 | |
| SCHEMBL25430574 | 0.84 | GAA (0.48) | GAASMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL16219037 | 0.82 | ALDH1A1 (0.48) | HSD17B10GAASMN1; SMN2POLBNOTUM | |
| SCHEMBL25428318 | 0.81 | GAA (0.48) | GAASMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL19722807 | 0.81 | ALDH1A1 (0.48) | CYP11B2GAASMN1; SMN2POLBMEN1 | |
| SCHEMBL15632473 | 0.80 | NOTUM (0.53) | CYP11B2NOTUMMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3703692-B1 | NOVEL SUBSTITUTED TETRAHYDROQUINOLIN COMPOUNDS AS INDOLEAMINE 2,3-DIOXYGENASE (IDO) INHIBITORS | MERCK SHARP & DOHME LLC (US) | 2025-07-23 | — | — | EP | claimed |