SCHEMBL31664271

SCHEMBL31664271

CC(C)(C)OC(=O)N1CC(c2ccc(C(F)(F)F)cn2)C1

nearest known ligand 0.48

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ SLC6A9 P48067 1/20 0.48
▸ MAPT P10636 1/20 0.47
▸ RORC P51449 1/20 0.46
▸ LIPE Q05469 5/20 0.45
▸ GPR119 Q8TDV5 2/20 0.43
▸ KDM4E B2RXH2 1/20 0.43
▸ HPGD P15428 1/20 0.43
▸ SMN1; SMN2 Q16637 1/20 0.43
▸ HRH3 Q9Y5N1 2/20 0.42
▸ EIF2AK4 Q9P2K8 1/20 0.42
▸ ALOX5AP P20292 1/20 0.41
▸ FEN1 P39748 1/20 0.41
▸ BCHE P06276 1/20 0.41
▸ TACR1 P25103 2/20 0.41
▸ MGLL Q99685 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29497039 0.90 KDM4E (0.45) SLC6A9MAPTRORCGPR119KDM4E
SCHEMBL25294988 0.90 KDM4E (0.45) SLC6A9MAPTRORCGPR119KDM4E
SCHEMBL5471664 0.88 GPR119 (0.49) MAPTLIPEGPR119KDM4EHPGD
SCHEMBL20743115 0.85 ALOX5AP (0.45) RORCKDM4ESMN1; SMN2ALOX5APFEN1
SCHEMBL14851551 0.83 KDM4E (0.46) MAPTGPR119KDM4E
SCHEMBL17729512 0.82 ALOX5AP (0.45) GPR119KDM4EALOX5APFEN1
SCHEMBL21381749 0.82 MEN1 (0.48) KDM4EHPGDSMN1; SMN2ALOX5APFEN1
SCHEMBL30395323 0.82 KDM4E (0.45) RORCGPR119KDM4EALOX5APFEN1
SCHEMBL23264041 0.82 KDM4E (0.45) RORCGPR119KDM4EALOX5APFEN1
SCHEMBL30567976 0.82 MEN1 (0.48) KDM4EHPGDSMN1; SMN2ALOX5APFEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4588920-A1 NOVEL PRMT5 INHIBITOR AND USE THEREOF Shanghai Apeiron Therapeutics Company Limited (CN) 2025-07-23 — — EP disclosed
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