Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HPGDS | O60760 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.41 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | F7 | P08709 | 1/20 | 0.40 |
| ▸ | F3 | P13726 | 1/20 | 0.40 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18296201 | 1.00 | NNMT (0.53) | NNMTSMN1; SMN2L3MBTL1KDM4EHPGDS | |
| SCHEMBL13490541 | 0.89 | NNMT (0.46) | NNMTSMN1; SMN2L3MBTL1KDM4E | |
| SCHEMBL22048049 | 0.89 | NNMT (0.46) | NNMTSMN1; SMN2L3MBTL1KDM4EHPGDS | |
| Hydrochloric Acid SCHEMBL20969010 | 0.87 | NNMT (0.45) | NNMTSMN1; SMN2L3MBTL1KDM4EMEN1 | |
| SCHEMBL30590918 | 0.83 | P4HA1 (0.59) | L3MBTL1MEN1KMT2ACNR2CYP2C9 | |
| SCHEMBL14822500 | 0.83 | P4HA1 (0.59) | L3MBTL1MEN1KMT2ACNR2CYP2C9 | |
| SCHEMBL29539403 | 0.81 | MEN1 (0.43) | L3MBTL1HPGDSMEN1KMT2ACNR2 | |
| SCHEMBL26107981 | 0.81 | MEN1 (0.43) | L3MBTL1HPGDSMEN1KMT2ACNR2 | |
| SCHEMBL18397093 | 0.81 | MEN1 (0.43) | L3MBTL1HPGDSMEN1KMT2ACNR2 | |
| SCHEMBL30016454 | 0.81 | HDAC2 (0.46) | L3MBTL1KDM4EHPGDSMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250236608-A1 | EGFR INHIBITORS | BLUEPRINT MEDICINES CORPORATION | 2025-07-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250236608-A1 | EGFR INHIBITORS | EGFR, ERBB2, ERBB3 | NNMT 3719/4885SMN1; SMN2 4587/4885L3MBTL1 4175/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.