Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.52 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.52 |
| ▸ | MTOR | P42345 | 1/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.51 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.48 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.47 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25143434 | 1.00 | MEN1 (0.55) | MEN1KMT2ASMN1; SMN2PIK3CAMTOR | |
| SCHEMBL31665506 | 0.86 | KMT2A (0.54) | MEN1KMT2ASMN1; SMN2RXFP1TSHR | |
| SCHEMBL31665584 | 0.82 | HPGD (0.63) | SMN1; SMN2PIK3CAMTORSORT1NPC1 | |
| SCHEMBL25143492 | 0.82 | HPGD (0.63) | SMN1; SMN2PIK3CAMTORSORT1NPC1 | |
| SCHEMBL24074161 | 0.82 | TSHR (0.74) | MEN1KMT2ARXFP1TSHRPOLB | |
| SCHEMBL12173061 | 0.81 | SORT1 (0.69) | MEN1KMT2APIK3CAMTORSORT1 | |
| SCHEMBL25063018 | 0.81 | KMT2A (0.66) | MEN1KMT2ASMN1; SMN2RXFP1NPC1 | |
| SCHEMBL31665146 | 0.81 | KMT2A (0.49) | MEN1KMT2ASMN1; SMN2RXFP1NPC1 | |
| SCHEMBL25142638 | 0.81 | KMT2A (0.49) | MEN1KMT2ASMN1; SMN2RXFP1NPC1 | |
| SCHEMBL25143324 | 0.80 | PIK3CA (0.60) | SMN1; SMN2PIK3CAMTORSORT1HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250235543-A1 | MODIFIED PROTEINS AND PROTEIN DEGRADERS | CULLGEN (SHANGHAI), INC. (CN) | 2025-07-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250235543-A1 | MODIFIED PROTEINS AND PROTEIN DEGRADERS | DDB1, DCLRE1A, TP53BP1 | MEN1 2854/4885KMT2A 2300/4885SMN1; SMN2 2871/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.