Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 4/20 | 0.60 |
| ▸ | RAB9A | P51151 | 4/20 | 0.60 |
| ▸ | TYK2 | P29597 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.56 |
| ▸ | MTOR | P42345 | 1/20 | 0.56 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.56 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.55 |
| ▸ | BLK | P51451 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25143492 | 1.00 | HPGD (0.63) | HPGDSMN1; SMN2L3MBTL1NPC1RAB9A | |
| SCHEMBL12173061 | 0.86 | SORT1 (0.69) | L3MBTL1CYP1A2PIK3CAMTORSORT1 | |
| SCHEMBL31110254 | 0.85 | PIK3CA (0.60) | SMN1; SMN2NPC1RAB9APIK3CAMTOR | |
| SCHEMBL25143324 | 0.85 | PIK3CA (0.60) | SMN1; SMN2NPC1RAB9APIK3CAMTOR | |
| SCHEMBL22340592 | 0.84 | KMT2A (0.63) | SMN1; SMN2NPC1RAB9ATP53MAPK1 | |
| SCHEMBL25143434 | 0.82 | MEN1 (0.55) | SMN1; SMN2NPC1RAB9APIK3CAMTOR | |
| SCHEMBL31665572 | 0.82 | MEN1 (0.55) | SMN1; SMN2NPC1RAB9APIK3CAMTOR | |
| SCHEMBL22323774 | 0.81 | MEN1 (0.67) | SMN1; SMN2NPC1RAB9AALOX15TP53 | |
| SCHEMBL13162689 | 0.81 | ALDH1A1 (0.70) | HPGDTYK2HTTMAPK1ALDH1A1 | |
| SCHEMBL31110262 | 0.81 | KCNQ3 (0.67) | SMN1; SMN2NPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250235543-A1 | MODIFIED PROTEINS AND PROTEIN DEGRADERS | CULLGEN (SHANGHAI), INC. (CN) | 2025-07-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250235543-A1 | MODIFIED PROTEINS AND PROTEIN DEGRADERS | DDB1, DCLRE1A, TP53BP1 | HPGD 3546/4885SMN1; SMN2 2871/4885L3MBTL1 1176/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.