Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.81 |
| ▸ | FTO | Q9C0B1 | 8/20 | 0.69 |
| ▸ | MAPT | P10636 | 5/20 | 0.69 |
| ▸ | MEN1 | O00255 | 3/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.69 |
| ▸ | HTT | P42858 | 2/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.69 |
| ▸ | HPGD | P15428 | 2/20 | 0.69 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.69 |
| ▸ | RECQL | P46063 | 1/20 | 0.69 |
| ▸ | BLM | P54132 | 1/20 | 0.69 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.69 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.69 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.69 |
| ▸ | LMNA | P02545 | 4/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3164943 | 0.97 | CYP3A4 (0.87) | CYP3A4FTOMAPTMEN1KMT2A | |
| Diethoxyflourescein SCHEMBL6404797 | 0.90 | CYP3A4 (1.00) | CYP3A4FTOMAPTMEN1KMT2A | |
| SCHEMBL20280256 | 0.89 | CYP3A4 (0.73) | CYP3A4FTOMAPTMEN1KMT2A | |
| SCHEMBL19153208 | 0.87 | FTO (0.75) | CYP3A4FTOMAPTMEN1KMT2A | |
| Naphthalene SCHEMBL3416984 | 0.87 | FTO (0.65) | CYP3A4FTOMAPTMEN1KMT2A | |
| SCHEMBL7567830 | 0.87 | CYP3A4 (0.69) | CYP3A4FTOMAPTMEN1KMT2A | |
| SCHEMBL31433112 | 0.86 | FTO (0.70) | CYP3A4FTOMAPTMEN1KMT2A | |
| SCHEMBL10103168 | 0.86 | FTO (0.70) | CYP3A4FTOMAPTMEN1KMT2A | |
| Fluorescein SCHEMBL3164935 | 0.86 | FTO (0.81) | CYP3A4FTOMAPTMEN1KMT2A | |
| SCHEMBL20280260 | 0.85 | FTO (0.69) | CYP3A4FTOMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1421213-B1 | LABELED NUCLEOSIDE POLYPHOSPHATES | GE HEALTHCARE BIO SCIENCES (US) | 2010-02-17 | — | — | EP | disclosed |
| EP-1597602-A4 | SOLID PHASE SEQUENCING | GE HEALTHCARE BIO SCIENCES (US) | 2009-07-22 | — | — | EP | disclosed |
| US-7041812-B2 | Labeled nucleoside polyphosphates | AMERSHAM BIOSCIENCES CORP (US) | 2006-05-09 | — | — | US | disclosed |
| EP-1597602-A2 | SOLID PHASE SEQUENCING | Amersham Biosciences Corp. (US) | 2005-11-23 | — | — | EP | disclosed |
| WO-2004071155-A2 | SOLID PHASE SEQUENCING | AMERSHAM BIOSCIENCES CORP (US) | 2004-08-26 | — | — | WO | disclosed |