Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 14/20 | 1.00 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.78 |
| ▸ | SYK | P43405 | 2/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
| ▸ | NOS3 | P29474 | 3/20 | 0.34 |
| ▸ | NOS1 | P29475 | 3/20 | 0.34 |
| ▸ | NOS2 | P35228 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25421666 | 0.87 | MC4R (1.00) | MC4RKCNH2 | |
| SCHEMBL30996495 | 0.87 | MC4R (1.00) | MC4RKCNH2 | |
| SCHEMBL30996497 | 0.87 | MC4R (0.86) | MC4RKCNH2 | |
| SCHEMBL31666907 | 0.86 | MC4R (0.76) | MC4RKCNH2SYKJAK2JAK1 | |
| SCHEMBL30457681 | 0.83 | MC4R (1.00) | MC4RKCNH2SYK | |
| SCHEMBL25422750 | 0.80 | MC4R (0.67) | MC4RKCNH2 | |
| SCHEMBL31666920 | 0.80 | MC4R (0.67) | MC4RKCNH2SYKJAK2JAK1 | |
| SCHEMBL31666919 | 0.79 | MC4R (0.70) | MC4RKCNH2SYKJAK2JAK1 | |
| SCHEMBL25437050 | 0.79 | MC4R (0.85) | MC4RKCNH2 | |
| SCHEMBL30458072 | 0.79 | MC4R (0.85) | MC4RKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4444708-B1 | MELANOCORTIN 4 RECEPTOR ANTAGONISTS AND USES THEREOF | PFIZER (US) | 2025-07-30 | — | — | EP | disclosed |