Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 11/20 | 0.67 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.65 |
| ▸ | CCNK | O75909 | 3/20 | 0.35 |
| ▸ | CDK12 | Q9NYV4 | 3/20 | 0.35 |
| ▸ | BTK | Q06187 | 2/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.32 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | CDK7 | P50613 | 1/20 | 0.32 |
| ▸ | CCNH | P51946 | 1/20 | 0.32 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25437281 | 0.89 | MC4R (0.55) | MC4RKCNH2CCNKCDK12BTK | |
| SCHEMBL31421655 | 0.88 | MC4R (0.64) | MC4RKCNH2BTK | |
| SCHEMBL30996531 | 0.88 | MC4R (0.64) | MC4RKCNH2BTK | |
| SCHEMBL25420312 | 0.85 | MC4R (0.55) | MC4RKCNH2CCNKCDK12BTK | |
| SCHEMBL25421659 | 0.84 | MC4R (0.49) | MC4RKCNH2CCNKCDK12BTK | |
| SCHEMBL31421667 | 0.82 | MC4R (0.63) | MC4RKCNH2BTK | |
| SCHEMBL31666907 | 0.81 | MC4R (0.76) | MC4RKCNH2PIK3CDPIK3R1 | |
| SCHEMBL31666895 | 0.80 | MC4R (1.00) | MC4RKCNH2 | |
| SCHEMBL25278377 | 0.80 | MC4R (0.59) | MC4RKCNH2CCNKCDK12BTK | |
| SCHEMBL25421666 | 0.79 | MC4R (1.00) | MC4RKCNH2BTKPIK3CDPIK3R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023105387-A1 | MELANOCORTIN 4 RECEPTOR ANTAGONISTS AND USES THEREOF | PFIZER INC. (US) | 2023-06-15 | — | — | WO | disclosed |