Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 16/20 | 0.76 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.74 |
| ▸ | JAK2 | O60674 | 2/20 | 0.35 |
| ▸ | JAK1 | P23458 | 2/20 | 0.35 |
| ▸ | JAK3 | P52333 | 2/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31666895 | 0.86 | MC4R (1.00) | MC4RKCNH2JAK2JAK1JAK3 | |
| SCHEMBL25421666 | 0.85 | MC4R (1.00) | MC4RKCNH2PIK3CDPIK3R1 | |
| SCHEMBL30996495 | 0.85 | MC4R (1.00) | MC4RKCNH2PIK3CDPIK3R1 | |
| SCHEMBL30996497 | 0.84 | MC4R (0.86) | MC4RKCNH2 | |
| SCHEMBL25422750 | 0.81 | MC4R (0.67) | MC4RKCNH2PIK3CDPIK3R1 | |
| SCHEMBL30457681 | 0.81 | MC4R (1.00) | MC4RKCNH2SYK | |
| SCHEMBL30996531 | 0.78 | MC4R (0.64) | MC4RKCNH2 | |
| SCHEMBL31421655 | 0.78 | MC4R (0.64) | MC4RKCNH2 | |
| SCHEMBL31666920 | 0.78 | MC4R (0.67) | MC4RKCNH2JAK2JAK1JAK3 | |
| SCHEMBL25437050 | 0.77 | MC4R (0.85) | MC4RKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4444708-B1 | MELANOCORTIN 4 RECEPTOR ANTAGONISTS AND USES THEREOF | PFIZER (US) | 2025-07-30 | — | — | EP | disclosed |