Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 11/20 | 0.72 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.71 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MLNR | O43193 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30457448 | 0.82 | MC4R (0.70) | MC4RKCNH2GFERALDH1A1SMN1; SMN2 | |
| SCHEMBL25272696 | 0.82 | MC4R (0.70) | MC4RKCNH2GFERALDH1A1SMN1; SMN2 | |
| SCHEMBL30457507 | 0.82 | MC4R (0.68) | MC4RKCNH2GFERALDH1A1SMN1; SMN2 | |
| SCHEMBL31666906 | 0.78 | MC4R (0.72) | MC4RKCNH2ALDH1A1SMN1; SMN2MLNR | |
| SCHEMBL31666899 | 0.76 | MC4R (0.65) | MC4RKCNH2ALDH1A1SMN1; SMN2MLNR | |
| SCHEMBL31666891 | 0.76 | MC4R (0.59) | MC4RKCNH2MLNRSYK | |
| SCHEMBL31666896 | 0.76 | MC4R (0.57) | MC4RKCNH2MLNRSYK | |
| SCHEMBL25228967 | 0.76 | MC4R (0.60) | MC4RKCNH2GFERALDH1A1SMN1; SMN2 | |
| SCHEMBL31666897 | 0.73 | KCNH2 (0.59) | MC4RKCNH2 | |
| SCHEMBL31666901 | 0.73 | MC4R (0.56) | MC4RKCNH2ALDH1A1SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4444708-B1 | MELANOCORTIN 4 RECEPTOR ANTAGONISTS AND USES THEREOF | PFIZER (US) | 2025-07-30 | — | — | EP | disclosed |