Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 7/20 | 0.72 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.72 |
| ▸ | HDAC4 | P56524 | 10/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | MLNR | O43193 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25277175 | 0.85 | MC4R (0.51) | MC4RKCNH2HDAC4HDAC6HDAC1 | |
| SCHEMBL31421699 | 0.82 | HDAC6 (0.64) | MC4RKCNH2HDAC4HDAC6HDAC1 | |
| SCHEMBL30457945 | 0.80 | HDAC4 (0.47) | MC4RKCNH2HDAC4HDAC6HDAC1 | |
| SCHEMBL30457507 | 0.79 | MC4R (0.68) | MC4RKCNH2LMNAMLNRCYP3A4 | |
| SCHEMBL30457448 | 0.79 | MC4R (0.70) | MC4RKCNH2LMNAMLNRCYP3A4 | |
| SCHEMBL25272696 | 0.79 | MC4R (0.70) | MC4RKCNH2LMNAMLNRCYP3A4 | |
| SCHEMBL31666902 | 0.78 | MC4R (0.72) | MC4RKCNH2LMNAMLNRCYP3A4 | |
| SCHEMBL31666899 | 0.77 | MC4R (0.65) | MC4RKCNH2LMNAMLNRCYP3A4 | |
| SCHEMBL25228967 | 0.75 | MC4R (0.60) | MC4RKCNH2LMNAMLNRCYP3A4 | |
| SCHEMBL25435475 | 0.72 | HDAC4 (0.53) | MC4RKCNH2HDAC4HDAC6HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4444708-B1 | MELANOCORTIN 4 RECEPTOR ANTAGONISTS AND USES THEREOF | PFIZER (US) | 2025-07-30 | — | — | EP | disclosed |