SCHEMBL31667345

SCHEMBL31667345

O=C1c2ccccc2C(c2ccccc2)N1Cc1ccc2[nH]c(=O)oc2c1

nearest known ligand 0.45

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ IL4I1 Q96RQ9 1/20 0.45
▸ HPGD P15428 2/20 0.41
▸ OGT O15294 1/20 0.40
▸ MEN1 O00255 2/20 0.40
▸ LMNA P02545 2/20 0.40
▸ MAPT P10636 2/20 0.40
▸ KMT2A Q03164 2/20 0.40
▸ MDM2 Q00987 3/20 0.39
▸ KDM1A O60341 1/20 0.38
▸ PTDSS1 P48651 2/20 0.38
▸ ALDH1A1 P00352 1/20 0.38
▸ TSHR P16473 1/20 0.38
▸ MAPK1 P28482 1/20 0.38
▸ HSD17B10 Q99714 1/20 0.38
▸ L3MBTL1 Q9Y468 1/20 0.38
▸ GRIN1 Q05586 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31667642 0.85 IL4I1 (0.46) IL4I1HPGDOGTMEN1LMNA
SCHEMBL31667115 0.85 IL4I1 (0.46) IL4I1HPGDOGTMEN1LMNA
SCHEMBL31666976 0.85 IL4I1 (0.46) IL4I1HPGDOGTMEN1LMNA
SCHEMBL31666930 0.85 MEN1 (0.45) IL4I1HPGDOGTMEN1LMNA
SCHEMBL31667679 0.85 MEN1 (0.45) IL4I1HPGDOGTMEN1LMNA
SCHEMBL31667717 0.85 MEN1 (0.45) IL4I1HPGDOGTMEN1LMNA
SCHEMBL31667224 0.83 IL4I1 (0.44) IL4I1HPGDOGTMEN1LMNA
SCHEMBL31667593 0.83 IL4I1 (0.42) IL4I1HPGDOGTMEN1LMNA
SCHEMBL31666945 0.83 IL4I1 (0.43) IL4I1HPGDOGTMEN1LMNA
SCHEMBL31667736 0.83 IL4I1 (0.43) IL4I1HPGDOGTMEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260078130-A1 NAMPT MODULATORS, PREPARATIONS, AND USES THEREOF SIRONAX LTD (KY) 2026-03-19 — — US disclosed
EP-4590674-A1 NAMPT MODULATORS, PREPARATIONS, AND USES THEREOF Sironax Ltd (KY) 2025-07-30 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260078130-A1 NAMPT MODULATORS, PREPARATIONS, AND USES THEREOF NAMPT, NNMT, SARM1 IL4I1 2872/4885HPGD 520/4885OGT 1193/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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