SCHEMBL31667383

SCHEMBL31667383

COc1ccc(-c2noc(N3CCC(C(=O)NCC4CCN(Cc5ccccn5)C4)CC3)n2)cc1

nearest known ligand 0.58

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 4/20 0.57
▸ KMT2A Q03164 4/20 0.57
▸ MAPT P10636 2/20 0.56
▸ LMNA P02545 2/20 0.56
▸ SMN1; SMN2 Q16637 2/20 0.56
▸ KDM4E B2RXH2 1/20 0.56
▸ ALDH1A1 P00352 1/20 0.56
▸ TP53 P04637 1/20 0.56
▸ HTT P42858 1/20 0.56
▸ HSD17B10 Q99714 1/20 0.56
▸ POLB P06746 1/20 0.49
▸ RAB9A P51151 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Formic Acid SCHEMBL25434989 0.97 MEN1 (0.54) MEN1KMT2AMAPTLMNASMN1; SMN2
SCHEMBL30584894 0.90 MEN1 (0.55) MEN1KMT2AMAPTLMNASMN1; SMN2
SCHEMBL30584734 0.90 MAPT (0.58) MEN1KMT2AMAPTLMNASMN1; SMN2
SCHEMBL31546397 0.89 MEN1 (0.60) MEN1KMT2AMAPTLMNASMN1; SMN2
SCHEMBL31667484 0.89 MEN1 (0.56) MEN1KMT2AMAPTLMNASMN1; SMN2
SCHEMBL30584870 0.89 MEN1 (0.56) MEN1KMT2AMAPTLMNASMN1; SMN2
SCHEMBL31546440 0.88 MEN1 (0.55) MEN1KMT2AMAPTLMNASMN1; SMN2
SCHEMBL30584997 0.88 MAPT (0.57) MEN1KMT2AMAPTLMNASMN1; SMN2
SCHEMBL31546392 0.88 MEN1 (0.59) MEN1KMT2AMAPTLMNASMN1; SMN2
SCHEMBL30584858 0.87 MEN1 (0.56) MEN1KMT2AMAPTLMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4463452-B1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC (US) 2025-07-30 — — EP claimed
EP-4463452-B1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC (US) 2025-07-30 — — EP disclosed
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